Selenium, Selenoenzymes, Oxidative Stress and Risk of Neoplastic Progression from Barrett's Esophagus: Results from Biomarkers and Genetic Variants

Yumie Takata; Alan R. Kristal; Regina M. Santella; Irena B. King; David J. Duggan; Johanna W. Lampe; Margaret P. Rayman; Patricia L. Blount; Brian J. Reid; Thomas L. Vaughan; Ulrike Peters

doi:10.1371/journal.pone.0038612

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Open Access

Peer-reviewed

Research Article

Selenium, Selenoenzymes, Oxidative Stress and Risk of Neoplastic Progression from Barrett's Esophagus: Results from Biomarkers and Genetic Variants

Yumie Takata,

Affiliation Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Alan R. Kristal,

Affiliation Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Regina M. Santella,

Affiliation Department of Environmental Health Sciences, Columbia University, New York, New York, United States of America
⨯
Irena B. King,

Affiliations Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, United States of America
⨯
David J. Duggan,

Affiliation Division of Genetic Basis of Human Disease, Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
Johanna W. Lampe,

Affiliation Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Margaret P. Rayman,

Affiliation Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
⨯
Patricia L. Blount,

Affiliation Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Brian J. Reid,

Affiliations Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Thomas L. Vaughan,

Affiliation Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Ulrike Peters

* E-mail: upeters@fhcrc.org

Affiliation Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯

Selenium, Selenoenzymes, Oxidative Stress and Risk of Neoplastic Progression from Barrett's Esophagus: Results from Biomarkers and Genetic Variants

Yumie Takata,
Alan R. Kristal,
Regina M. Santella,
Irena B. King,
David J. Duggan,
Johanna W. Lampe,
Margaret P. Rayman,
Patricia L. Blount,
Brian J. Reid,
Thomas L. Vaughan

Published: June 8, 2012
https://doi.org/10.1371/journal.pone.0038612

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Selenium
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Cancer risk factors
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Aneuploidy
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Esophageal cancer
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