Design Novel Dual Agonists for Treating Type-2 Diabetes by Targeting Peroxisome Proliferator-Activated Receptors with Core Hopping Approach

• Ying Ma ,

  Contributed equally to this work with: Ying Ma, Shu-Qing Wang

  Affiliation Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China

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• Shu-Qing Wang ,

  Contributed equally to this work with: Ying Ma, Shu-Qing Wang

  * E-mail: sqwang@gordonlifescience.org (SQW); wangrunling@tijmu.edu.cn (RLW)

  Affiliations Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China, Gordon Life Science Institute, San Diego, California, United States of America

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• Wei-Ren Xu,

  Affiliation Tianjin Institute of Pharmaceutical Research (TIPR), Tianjin, China

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• Run-Ling Wang ,

  * E-mail: sqwang@gordonlifescience.org (SQW); wangrunling@tijmu.edu.cn (RLW)

  Affiliation Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China

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• Kuo-Chen Chou

  Affiliation Gordon Life Science Institute, San Diego, California, United States of America

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