Three New Alpha1-Antitrypsin Deficiency Variants Help to Define a C-Terminal Region Regulating Conformational Change and Polymerization

• Anna M. Fra ,

  * E-mail: fra@med.unibs.it

  Affiliation Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy

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• Bibek Gooptu,

  Affiliation Institute of Structural Molecular Biology/Crystallography, Birkbeck College, University of London, London, United Kingdom

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• Ilaria Ferrarotti,

  Affiliation Department of Molecular Medicine, University of Pavia, Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy

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• Elena Miranda,

  Affiliation Department of Biology and Biotechnology ‘Charles Darwin’ and Pasteur Institute, Cenci Bolognetti Foundation, University of Rome ‘La Sapienza’, Rome, Italy

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• Roberta Scabini,

  Affiliation Department of Molecular Medicine, University of Pavia, Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy

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• Riccardo Ronzoni,

  Affiliation Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy

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• Federica Benini,

  Current address: Division of Internal Medicine, Desenzano Hospital, Brescia, Italy

  Affiliation Division of Internal Medicine, Spedali Civili, Brescia, Italy

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• Luciano Corda,

  Affiliation Division of Internal Medicine, Spedali Civili, Brescia, Italy

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• Daniela Medicina,

  Affiliation Department of Pathology, Spedali Civili, Brescia, Italy

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• Maurizio Luisetti,

  Affiliation Department of Molecular Medicine, University of Pavia, Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy

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• Luisa Schiaffonati

  Affiliation Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy

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