Visualization of Genomic Changes by Segmented Smoothing Using an L0 Penalty

Open Access

Peer-reviewed

Research Article

Visualization of Genomic Changes by Segmented Smoothing Using an L₀ Penalty

Ralph C. A. Rippe ,

* E-mail: R.C.A.Rippe@lumc.nl

Affiliation Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
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Jacqueline J. Meulman,

Affiliation Institute of Mathematics, Leiden University, Leiden, The Netherlands
⨯
Paul H. C. Eilers

Affiliation Department of Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
⨯

Copy number variation
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Cancers and neoplasms
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Chromosome mapping
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Simulation and modeling
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Computer software
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Normal distribution
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Algorithms
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Human genomics
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