Demethylation of the Coding Region Triggers the Activation of the Human Testis-Specific PDHA2 Gene in Somatic Tissues

Open Access

Peer-reviewed

Research Article

Ana Pinheiro,

Affiliation Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal
⨯
Maria João Nunes,

Affiliation Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal
⨯
Inês Milagre,

Affiliation Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal
⨯
Elsa Rodrigues,

Affiliations Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal, Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
⨯
Maria João Silva,

Affiliations Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal, Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
⨯
Isabel Tavares de Almeida,

Affiliations Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal, Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
⨯
Isabel Rivera

* E-mail: iarivera@ff.ul.pt

Affiliations Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Lisbon, Portugal, Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
⨯

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DNA methylation
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Gene expression
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Messenger RNA
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DNA transcription
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Gene regulation
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Luciferase
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Promoter regions
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Polymerase chain reaction
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