Ubiquitous [Na+]i/[K+]i-Sensitive Transcriptome in Mammalian Cells: Evidence for Ca2+i-Independent Excitation-Transcription Coupling

Open Access

Peer-reviewed

Research Article

Ubiquitous [Na⁺]_i/[K⁺]_i-Sensitive Transcriptome in Mammalian Cells: Evidence for Ca²⁺_i-Independent Excitation-Transcription Coupling

Svetlana V. Koltsova,

Affiliations Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) – Technopôle Angus, Montreal, PQ, Canada, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia
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Yulia Trushina,

Affiliation Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia
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Mounsif Haloui,

Affiliation Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) – Technopôle Angus, Montreal, PQ, Canada
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Olga A. Akimova,

Affiliations Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia, Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia
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Johanne Tremblay,

Affiliations Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) – Technopôle Angus, Montreal, PQ, Canada, Department of Medicine, Université de Montréal, Montreal, PQ, Canada
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Pavel Hamet,

Affiliations Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) – Technopôle Angus, Montreal, PQ, Canada, Department of Medicine, Université de Montréal, Montreal, PQ, Canada
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Sergei N. Orlov

* E-mail: sergei.n.orlov@umontreal.ca

Affiliations Centre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) – Technopôle Angus, Montreal, PQ, Canada, Department of Medicine, Université de Montréal, Montreal, PQ, Canada
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Gene expression
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Gene regulation
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Transcriptome analysis
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Regulator genes
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Phosphatases
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Transcriptional control
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HeLa cells
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Transcription factors
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