Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

Hiroshi Nishimune; Tomohiro Numata; Jie Chen; Yudai Aoki; Yonghong Wang; Miranda P. Starr; Yasuo Mori; John A. Stanford

doi:10.1371/journal.pone.0038029

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Peer-reviewed

Research Article

Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

Hiroshi Nishimune ,

Contributed equally to this work with: Hiroshi Nishimune, Tomohiro Numata

* E-mail: hnishimune@kumc.edu (HN); mori@sbchem.kyoto-u.ac.jp (YM); JSTANFORD@kumc.edu (JAS)

Affiliation Department of Anatomy and Cell Biology, University of Kansas Medical School, Kansas City, Kansas, United States of America
⨯
Tomohiro Numata ,

Contributed equally to this work with: Hiroshi Nishimune, Tomohiro Numata

Affiliation Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto, Japan
⨯
Jie Chen,

Affiliation Department of Anatomy and Cell Biology, University of Kansas Medical School, Kansas City, Kansas, United States of America
⨯
Yudai Aoki,

Affiliation Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto, Japan
⨯
Yonghong Wang,

Affiliation Department of Molecular & Integrative Physiology, University of Kansas Medical School, Kansas City, Kansas, United States of America
⨯
Miranda P. Starr,

Affiliation Department of Molecular & Integrative Physiology, University of Kansas Medical School, Kansas City, Kansas, United States of America
⨯
Yasuo Mori ,

* E-mail: hnishimune@kumc.edu (HN); mori@sbchem.kyoto-u.ac.jp (YM); JSTANFORD@kumc.edu (JAS)

Affiliation Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto, Japan
⨯
John A. Stanford

* E-mail: hnishimune@kumc.edu (HN); mori@sbchem.kyoto-u.ac.jp (YM); JSTANFORD@kumc.edu (JAS)

Affiliation Department of Molecular & Integrative Physiology, University of Kansas Medical School, Kansas City, Kansas, United States of America
⨯

Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

Hiroshi Nishimune,
Tomohiro Numata,
Jie Chen,
Yudai Aoki,
Yonghong Wang,
Miranda P. Starr,
Yasuo Mori,
John A. Stanford

Published: June 6, 2012
https://doi.org/10.1371/journal.pone.0038029

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