Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease

José A. Agúndez; Elena García-Martin; María L. Maestro; Francisca Cuenca; Carmen Martínez; Luis Ortega; Miguel Carballo; Marta Vidaurreta; Marta Agreda; Gabriela Díaz-Zelaya; Avelina Suárez; Manuel Díaz-Rubio; José M. Ladero

doi:10.1371/journal.pone.0037998

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Open Access

Peer-reviewed

Research Article

Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease

José A. Agúndez,

Affiliation Department of Pharmacology, University of Extremadura, Cáceres, Spain
⨯
Elena García-Martin,

Affiliation Department of Biochemistry & Molecular Biology, University of Extremadura, Cáceres, Spain
⨯
María L. Maestro,

Affiliation Genomics Unit, Service of Clinical Biochemistry, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Francisca Cuenca,

Affiliation Liver Unit, Service of Gastroenterology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Carmen Martínez,

Affiliation Department of Pharmacology, University of Extremadura, Cáceres, Spain
⨯
Luis Ortega,

Affiliation Service of Pathology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Miguel Carballo,

Affiliation Laboratory of Molecular Genetics, Hospital de Terrassa, Terrassa (Barcelona), Spain
⨯
Marta Vidaurreta,

Affiliation Genomics Unit, Service of Clinical Biochemistry, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Marta Agreda,

Affiliation Liver Unit, Service of Gastroenterology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Gabriela Díaz-Zelaya,

Affiliation Service of Pathology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
Avelina Suárez,

Affiliation Service of Clinical Microbiology, Hospital Clínico San Carlos (IdISCC), Madrid, Spain
⨯
Manuel Díaz-Rubio,

Affiliation Liver Unit, Service of Gastroenterology, Hospital Clínico San Carlos, Department of Medicine, Medical School, Universidad Complutense, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯
José M. Ladero

* E-mail: jladero.hcsc@salud.madrid.org

Affiliation Liver Unit, Service of Gastroenterology, Hospital Clínico San Carlos, Department of Medicine, Medical School, Universidad Complutense, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain
⨯

Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease

José A. Agúndez,
Elena García-Martin,
María L. Maestro,
Francisca Cuenca,
Carmen Martínez,
Luis Ortega,
Miguel Carballo,
Marta Vidaurreta,
Marta Agreda,
Gabriela Díaz-Zelaya

Published: May 29, 2012
https://doi.org/10.1371/journal.pone.0037998

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Genome-wide association studies
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Single nucleotide polymorphisms
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