Tuning the Drug Efflux Activity of an ABC Transporter in vivo by in vitro Selected DARPin Binders

• Markus A. Seeger ,

  * E-mail: m.seeger@bioc.uzh.ch (MAS); hwv20@cam.ac.uk (HWvV)

  Affiliations Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Anshumali Mittal,

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Saroj Velamakanni,

  Affiliation Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom

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• Michael Hohl,

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Stefan Schauer,

  Affiliation Functional Genomics Center Zurich, University of Zurich, Zurich, Switzerland

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• Ihsene Salaa,

  Affiliation Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom

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• Markus G. Grütter,

  Affiliation Department of Biochemistry, University of Zurich, Zurich, Switzerland

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• Hendrik W. van Veen

  * E-mail: m.seeger@bioc.uzh.ch (MAS); hwv20@cam.ac.uk (HWvV)

  Affiliation Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom

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