p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

Joern Henze; Thomas Mühlenberg; Susanne Simon; Florian Grabellus; Brian Rubin; Georg Taeger; Martin Schuler; Juergen Treckmann; Maria Debiec-Rychter; Takahiro Taguchi; Jonathan A. Fletcher; Sebastian Bauer

doi:10.1371/journal.pone.0037776

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Open Access

Peer-reviewed

Research Article

p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

Joern Henze,

Affiliation Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Thomas Mühlenberg,

Affiliation Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Susanne Simon,

Affiliation Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Florian Grabellus,

Affiliation Department of Pathology and Neuropathology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Brian Rubin,

Affiliation Department of Molecular Genetics and Anatomic Pathology, Lerner Research Institute, Cleveland Clinic, Taussig Cancer Center, Cleveland, Ohio, United States of America
⨯
Georg Taeger,

Affiliation Department of Trauma and Orthopedic Surgery, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Martin Schuler,

Affiliation Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Juergen Treckmann,

Affiliation Department of Visceral and Transplant Surgery, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯
Maria Debiec-Rychter,

Affiliation Department of Human Genetics, University of Leuven, Leuven, Belgium
⨯
Takahiro Taguchi,

Affiliation Division of Human Health and Medical Science, Graduate School of Kuroshio Science, Kochi University, Nankoku, Kochi, Japan
⨯
Jonathan A. Fletcher,

Affiliation Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Sebastian Bauer

* E-mail: sebastian.bauer@uk-essen.de

Affiliation Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen Medical School, Essen, Germany
⨯

p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

Joern Henze,
Thomas Mühlenberg,
Susanne Simon,
Florian Grabellus,
Brian Rubin,
Georg Taeger,
Martin Schuler,
Juergen Treckmann,
Maria Debiec-Rychter,
Takahiro Taguchi

Published: May 25, 2012
https://doi.org/10.1371/journal.pone.0037776

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