EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

Yuan Xu; Yuan Li; Ying Pang; Min Ling; Lu Shen; Xiaojun Yang; Jianping Zhang; Jianwei Zhou; Xinru Wang; Qizhan Liu

doi:10.1371/journal.pone.0037765

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Open Access

Peer-reviewed

Research Article

EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

Yuan Xu ,

Contributed equally to this work with: Yuan Xu, Yuan Li, Ying Pang

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Yuan Li ,

Contributed equally to this work with: Yuan Xu, Yuan Li, Ying Pang

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Ying Pang ,

Contributed equally to this work with: Yuan Xu, Yuan Li, Ying Pang

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Min Ling,

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Lu Shen,

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Xiaojun Yang,

Affiliation Department of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Jianping Zhang,

Affiliation Department of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Jianwei Zhou,

Affiliation The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Xinru Wang,

Affiliation The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯
Qizhan Liu

* E-mail: drqzliu@hotmail.com

Affiliations Institute of Toxicology, Nanjing Medical University, Nanjing, People's Republic of China, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China
⨯

EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

Yuan Xu,
Yuan Li,
Ying Pang,
Min Ling,
Lu Shen,
Xiaojun Yang,
Jianping Zhang,
Jianwei Zhou,
Xinru Wang,
Qizhan Liu

Published: May 25, 2012
https://doi.org/10.1371/journal.pone.0037765

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