Protein-Protein Interaction Site Predictions with Three-Dimensional Probability Distributions of Interacting Atoms on Protein Surfaces

Ching-Tai Chen; Hung-Pin Peng; Jhih-Wei Jian; Keng-Chang Tsai; Jeng-Yih Chang; Ei-Wen Yang; Jun-Bo Chen; Shinn-Ying Ho; Wen-Lian Hsu; An-Suei Yang

doi:10.1371/journal.pone.0037706

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Open Access

Peer-reviewed

Research Article

Protein-Protein Interaction Site Predictions with Three-Dimensional Probability Distributions of Interacting Atoms on Protein Surfaces

Ching-Tai Chen,

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan, Institute of Bioinformatics and Systems Biology, National Chiao-Tung University, Hsinchu, Taiwan, Institute of Information Science, Academia Sinica, Taipei, Taiwan, Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan
⨯
Hung-Pin Peng,

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan, Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan, Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan
⨯
Jhih-Wei Jian,

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan, Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan, Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan
⨯
Keng-Chang Tsai,

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan
⨯
Jeng-Yih Chang,

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan
⨯
Ei-Wen Yang,

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan, Institute of Information Science, Academia Sinica, Taipei, Taiwan
⨯
Jun-Bo Chen,

Affiliations Genomics Research Center, Academia Sinica, Taipei, Taiwan, Department of Computer Science, National Tsing-Hua University, Hsinchu, Taiwan
⨯
Shinn-Ying Ho,

Affiliation Institute of Bioinformatics and Systems Biology, National Chiao-Tung University, Hsinchu, Taiwan
⨯
Wen-Lian Hsu ,

* E-mail: yangas@gate.sinica.edu.tw (AY); hsu@iis.sinica.edu.tw (WH)

Affiliation Institute of Information Science, Academia Sinica, Taipei, Taiwan
⨯
An-Suei Yang

* E-mail: yangas@gate.sinica.edu.tw (AY); hsu@iis.sinica.edu.tw (WH)

Affiliation Genomics Research Center, Academia Sinica, Taipei, Taiwan
⨯

Protein-Protein Interaction Site Predictions with Three-Dimensional Probability Distributions of Interacting Atoms on Protein Surfaces

Ching-Tai Chen,
Hung-Pin Peng,
Jhih-Wei Jian,
Keng-Chang Tsai,
Jeng-Yih Chang,
Ei-Wen Yang,
Jun-Bo Chen,
Shinn-Ying Ho,
Wen-Lian Hsu,
An-Suei Yang

Published: June 6, 2012
https://doi.org/10.1371/journal.pone.0037706

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Protein structure prediction
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Machine learning
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Protein structure
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Proteomic databases
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Machine learning algorithms
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Forecasting
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Protein-protein interactions
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Protein structure comparison
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