Hepatitis C Virus Sensitizes Host Cells to TRAIL-Induced Apoptosis by Up-Regulating DR4 and DR5 via a MEK1-Dependent Pathway

Open Access

Peer-reviewed

Research Article

Zhongfan Deng,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
⨯
Huijuan Yan,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
⨯
Jiajie Hu,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
⨯
Shengwei Zhang,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
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Peng Peng,

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
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Qingzhen Liu ,

* E-mail: qzhliu@whu.edu.cn (QL); dguo@whu.edu.cn (DG)

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
⨯
Deyin Guo

* E-mail: qzhliu@whu.edu.cn (QL); dguo@whu.edu.cn (DG)

Affiliation State Key Laboratory of Virology and The Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China
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Apoptosis
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Hepatitis C virus
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Small interfering RNA
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Luciferase
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Transfection
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Transcription factors
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Host cells
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Plasmid construction
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