Prenatal Hyperandrogenization Induces Metabolic and Endocrine Alterations Which Depend on the Levels of Testosterone Exposure

Sabrina Amalfi; Leandro Martín Velez; María Florencia Heber; Susana Vighi; Silvana Rocío Ferreira; Adriana Vega Orozco; Omar Pignataro; Alicia Beatriz Motta

doi:10.1371/journal.pone.0037658

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Peer-reviewed

Research Article

Prenatal Hyperandrogenization Induces Metabolic and Endocrine Alterations Which Depend on the Levels of Testosterone Exposure

Sabrina Amalfi,

Affiliation Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Leandro Martín Velez,

Affiliation Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
María Florencia Heber,

Affiliation Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Susana Vighi,

Affiliation Departamento de Patología, Hospital de Clínicas, Buenos Aires, Argentina
⨯
Silvana Rocío Ferreira,

Affiliation Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Adriana Vega Orozco,

Affiliation Laboratorio de Investigaciones Biomédicas, Instituto de Biología y Medicina de Cuyo, Buenos Aires, Argentina
⨯
Omar Pignataro,

Affiliation Laboratorio de Endocrinología Molecular y Transducción de Señales, Instituto de Biología y Medicina Experimental, Nacional de Investigaciones Científicas y Técnicas, Buenos Aries, Argentina
⨯
Alicia Beatriz Motta

* E-mail: aliciabmotta@yahoo.com.ar

Affiliation Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯

Prenatal Hyperandrogenization Induces Metabolic and Endocrine Alterations Which Depend on the Levels of Testosterone Exposure

Sabrina Amalfi,
Leandro Martín Velez,
María Florencia Heber,
Susana Vighi,
Silvana Rocío Ferreira,
Adriana Vega Orozco,
Omar Pignataro,
Alicia Beatriz Motta

Published: May 24, 2012
https://doi.org/10.1371/journal.pone.0037658

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Testosterone
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Polycystic ovary syndrome
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Protein expression
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Androgens
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