A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

Hua Yu; Jianxin Chen; Xue Xu; Yan Li; Huihui Zhao; Yupeng Fang; Xiuxiu Li; Wei Zhou; Wei Wang; Yonghua Wang

doi:10.1371/journal.pone.0037608

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Open Access

Peer-reviewed

Research Article

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

Hua Yu ,

Contributed equally to this work with: Hua Yu, Jianxin Chen

Affiliation Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China
⨯
Jianxin Chen ,

Contributed equally to this work with: Hua Yu, Jianxin Chen

Affiliation Beijing University of Chinese Medicine, ChaoYang District, Beijing, China
⨯
Xue Xu,

Affiliation Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China
⨯
Yan Li,

Affiliation Department of Chemical Engineering and Materials Science, Dalian University of Technology, Dalian, China
⨯
Huihui Zhao,

Affiliation Beijing University of Chinese Medicine, ChaoYang District, Beijing, China
⨯
Yupeng Fang,

Affiliation Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China
⨯
Xiuxiu Li,

Affiliation Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China
⨯
Wei Zhou,

Affiliation Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China
⨯
Wei Wang ,

* E-mail: wangwei@bucm.edu.cn (WW); yh_wang@nwsuaf.edu.cn (YHW)

Affiliation Beijing University of Chinese Medicine, ChaoYang District, Beijing, China
⨯
Yonghua Wang

* E-mail: wangwei@bucm.edu.cn (WW); yh_wang@nwsuaf.edu.cn (YHW)

Affiliations Bioinformatics Center, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China
⨯

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

Hua Yu,
Jianxin Chen,
Xue Xu,
Yan Li,
Huihui Zhao,
Yupeng Fang,
Xiuxiu Li,
Wei Zhou,
Wei Wang,
Yonghua Wang

Published: May 30, 2012
https://doi.org/10.1371/journal.pone.0037608

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06 Jun 2012
12:57 GMT
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Chemistry-to-protein realatioships in DrugBank Posted by cdsouthan on 06 Jun 2012 at 12:57 GMT

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