pKa Modulation of the Acid/Base Catalyst within GH32 and GH68: A Role in Substrate/Inhibitor Specificity?

• Shuguang Yuan,

  Affiliations Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, KU Leuven, Heverlee, Belgium, Laboratory for Biomolecular Modelling, Department of Chemistry, Division of Biochemistry, Molecular and Structural Biology, KU Leuven, Heverlee, Belgium

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• Katrien Le Roy,

  Affiliation Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, KU Leuven, Heverlee, Belgium

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• Tom Venken,

  Affiliation Laboratory for Biomolecular Modelling, Department of Chemistry, Division of Biochemistry, Molecular and Structural Biology, KU Leuven, Heverlee, Belgium

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• Willem Lammens,

  Affiliation Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, KU Leuven, Heverlee, Belgium

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• Wim Van den Ende ,

  * E-mail: wim.vandenende@bio.kuleuven.be (WV); marc.demaeyer@fys.kuleuven.be (MDM)

  Affiliation Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, KU Leuven, Heverlee, Belgium

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• Marc De Maeyer

  * E-mail: wim.vandenende@bio.kuleuven.be (WV); marc.demaeyer@fys.kuleuven.be (MDM)

  Affiliation Laboratory for Biomolecular Modelling, Department of Chemistry, Division of Biochemistry, Molecular and Structural Biology, KU Leuven, Heverlee, Belgium

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