Cataract-Causing Defect of a Mutant γ-Crystallin Proceeds through an Aggregation Pathway Which Bypasses Recognition by the α-Crystallin Chaperone

Open Access

Peer-reviewed

Research Article

Kate L. Moreau,

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Jonathan A. King

* E-mail: jaking@mit.edu

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Cataracts
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Optical lenses
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Protein folding
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Amino acid substitution
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Denaturation
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Fluorescence
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Protein interactions
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Turbidity
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