Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells

Xinghua Liu; Bo Zhang; Yan Guo; Qi Liang; Changyao Wu; Lei Wu; Kaixiong Tao; Guobin Wang; Jianying Chen

doi:10.1371/journal.pone.0037096

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Open Access

Peer-reviewed

Research Article

Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells

Xinghua Liu ,

Contributed equally to this work with: Xinghua Liu, Bo Zhang

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Bo Zhang ,

Contributed equally to this work with: Xinghua Liu, Bo Zhang

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Yan Guo,

Affiliation Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Qi Liang,

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Changyao Wu,

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Lei Wu,

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Kaixiong Tao,

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Guobin Wang ,

* E-mail: unionchen@yahoo.com.cn (JC); union_wang.guobin@yahoo.com.cn (GW)

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Jianying Chen

* E-mail: unionchen@yahoo.com.cn (JC); union_wang.guobin@yahoo.com.cn (GW)

Affiliation Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯

Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells

Xinghua Liu,
Bo Zhang,
Yan Guo,
Qi Liang,
Changyao Wu,
Lei Wu,
Kaixiong Tao,
Guobin Wang,
Jianying Chen

Published: May 16, 2012
https://doi.org/10.1371/journal.pone.0037096

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Small interfering RNA
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Gastric cancer
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