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Open Access

Peer-reviewed

Research Article

NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye

Xiaobo Zhang,

Affiliations Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China
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Eugene A. Volpe,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Niral B. Gandhi,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Chris S. Schaumburg,

Affiliation Department of Biological Sciences, Allergan Inc., Irvine, California, United States of America
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Karyn F. Siemasko,

Affiliation Department of Biological Sciences, Allergan Inc., Irvine, California, United States of America
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Solherny B. Pangelinan,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Scott D. Kelly,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Adrian C. Hayday,

Affiliation Department of Immunobiology, King’s College London at Guy’s Hospital, London, United Kingdom
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De-Quan Li,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Michael E. Stern,

Affiliations Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Biological Sciences, Allergan Inc., Irvine, California, United States of America
⨯
Jerry Y. Niederkorn,

Affiliation Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
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Stephen C. Pflugfelder,

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
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Cintia S. De Paiva

* E-mail: cintiadp@bcm.tmc.edu

Affiliation Department of Ophthalmology, Ocular Surface Center, Baylor College of Medicine, Houston, Texas, United States of America
⨯

NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye

Xiaobo Zhang,
Eugene A. Volpe,
Niral B. Gandhi,
Chris S. Schaumburg,
Karyn F. Siemasko,
Solherny B. Pangelinan,
Scott D. Kelly,
Adrian C. Hayday,
De-Quan Li,
Michael E. Stern

x

Published: May 8, 2012
https://doi.org/10.1371/journal.pone.0036822

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Flow cytometry
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NK cells
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Enzyme-linked immunoassays
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Lymphocytes
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T cells
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