Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

Open Access

Peer-reviewed

Research Article

Bryan S. Briney,

Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Jordan R. Willis,

Affiliation Chemical and Physical Biology Program of Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
James E. Crowe Jr.

* E-mail: james.crowe@vanderbilt.edu

Affiliations Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Antibodies
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Blood
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B cells
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Protein sequencing
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Antibody production
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HIV
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Insertion mutation
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Genetics
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