Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Scott A. Hoose; Camille Duran; Indranil Malik; Shabnam Eslamfam; Samantha C. Shasserre; S. Sabina Downing; Evelyn M. Hoover; Katherine E. Dowd; Roger Smith III; Michael Polymenis

doi:10.1371/journal.pone.0036503

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Peer-reviewed

Research Article

Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Scott A. Hoose,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Camille Duran,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Indranil Malik,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Shabnam Eslamfam,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Samantha C. Shasserre,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
S. Sabina Downing,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Evelyn M. Hoover,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Katherine E. Dowd,

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯
Roger Smith III,

Affiliation Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America
⨯
Michael Polymenis

* E-mail: polymenis@tamu.edu

Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
⨯

Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Scott A. Hoose,
Camille Duran,
Indranil Malik,
Shabnam Eslamfam,
Samantha C. Shasserre,
S. Sabina Downing,
Evelyn M. Hoover,
Katherine E. Dowd,
Roger Smith III,
Michael Polymenis

Published: May 2, 2012
https://doi.org/10.1371/journal.pone.0036503

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