Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

• Lihong Wang,

  Affiliations Department of Pediatrics, Vanderbilt University Medical Center and the Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, United States of America, Cancer Research Center, Xiamen University Medical College, Xiamen, P. R. China

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• Liping Liu,

  Affiliation Department of Pediatrics, Vanderbilt University Medical Center and the Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, United States of America

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• Yan Shi,

  Current address: School of Life Sciences, Xiamen University, Xiamen, P. R. China

  Affiliation Department of Pediatrics, Vanderbilt University Medical Center and the Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, United States of America

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• Hanwei Cao,

  Current address: Cancer Research Center, Xiamen University Medical College, Xiamen, P. R. China

  Affiliation Department of Pediatrics, Vanderbilt University Medical Center and the Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, United States of America

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• Rupesh Chaturvedi,

  Affiliation Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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• M. Wade Calcutt,

  Affiliation Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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• Tianhui Hu,

  Affiliation Cancer Research Center, Xiamen University Medical College, Xiamen, P. R. China

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• Xiubao Ren,

  Affiliation Department of Biotherapy, Cancer Institute & Hospital, Tianjin Medical University, Tianjin, P. R. China

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• Keith T. Wilson,

  Affiliations Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America

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• D. Brent Polk,

  Affiliation Department of Pediatrics, University of Southern California and Children’s Hospital Los Angeles, Los Angeles, California, United States of America

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• Fang Yan

  * E-mail: fang.yan@vanderbilt.edu

  Affiliations Department of Pediatrics, Vanderbilt University Medical Center and the Monroe Carell Jr. Children’s Hospital at Vanderbilt, Nashville, Tennessee, United States of America, Department of Biotherapy, Cancer Institute & Hospital, Tianjin Medical University, Tianjin, P. R. China

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