Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

Andy Ka-Leung Ng; Wai-Hon Chan; Sze-Ting Choi; Mandy Ka-Han Lam; Kwok-Fai Lau; Paul Kay-Sheung Chan; Shannon Wing-Ngor Au; Ervin Fodor; Pang-Chui Shaw

doi:10.1371/journal.pone.0036415

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Peer-reviewed

Research Article

Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

Andy Ka-Leung Ng,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Wai-Hon Chan,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Sze-Ting Choi,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Mandy Ka-Han Lam,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Kwok-Fai Lau,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Paul Kay-Sheung Chan,

Affiliation Department of Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Shannon Wing-Ngor Au,

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯
Ervin Fodor,

Affiliation Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
⨯
Pang-Chui Shaw

* E-mail: pcshaw@cuhk.edu.hk

Affiliation Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
⨯

Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

Andy Ka-Leung Ng,
Wai-Hon Chan,
Sze-Ting Choi,
Mandy Ka-Han Lam,
Kwok-Fai Lau,
Paul Kay-Sheung Chan,
Shannon Wing-Ngor Au,
Ervin Fodor,
Pang-Chui Shaw

Published: May 3, 2012
https://doi.org/10.1371/journal.pone.0036415

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293T cells
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