A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

Ruojing Yang; Raul G. Lacson; Gino Castriota; Xiaohua D. Zhang; Yaping Liu; Wenqing Zhao; Monica Einstein; Luiz Miguel Camargo; Sajjad Qureshi; Kenny K. Wong; Bei B. Zhang; Marc Ferrer; Joel P. Berger

doi:10.1371/journal.pone.0036384

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Open Access

Peer-reviewed

Research Article

A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

Ruojing Yang ,

* E-mail: ruojing_yang@merck.com (RY); joel_berger@merck.com (JPB)

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Raul G. Lacson,

Affiliation Cell Based HTS, Merck Research Laboratories, North Wales, Pennsylvania, United States of America
⨯
Gino Castriota,

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Xiaohua D. Zhang,

Affiliation Biometrics Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America
⨯
Yaping Liu,

Affiliation Cell Based HTS, Merck Research Laboratories, North Wales, Pennsylvania, United States of America
⨯
Wenqing Zhao,

Affiliation Department of Guided Solutions, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Monica Einstein,

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Luiz Miguel Camargo,

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Sajjad Qureshi,

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Kenny K. Wong,

Affiliation Department of Atherosclerosis, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Bei B. Zhang,

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯
Marc Ferrer,

Affiliation Cell Based HTS, Merck Research Laboratories, North Wales, Pennsylvania, United States of America
⨯
Joel P. Berger

* E-mail: ruojing_yang@merck.com (RY); joel_berger@merck.com (JPB)

Affiliation Department of Metebolic Disorders-Diabetes, Merck Research Laboratories, Rahway, New Jersey, United States of America
⨯

A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

Ruojing Yang,
Raul G. Lacson,
Gino Castriota,
Xiaohua D. Zhang,
Yaping Liu,
Wenqing Zhao,
Monica Einstein,
Luiz Miguel Camargo,
Sajjad Qureshi,
Kenny K. Wong

Published: May 9, 2012
https://doi.org/10.1371/journal.pone.0036384

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