The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages

Sankaralingam Saikolappan; Jaymie Estrella; Smitha J. Sasindran; Arshad Khan; Lisa Y. Armitige; Chinnaswamy Jagannath; Subramanian Dhandayuthapani

doi:10.1371/journal.pone.0036198

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Research Article

The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages

Sankaralingam Saikolappan,

Affiliation Regional Academic Health Center and Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, Edinburg, Texas, United States of America
⨯
Jaymie Estrella,

Affiliation Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Smitha J. Sasindran,

Affiliation Regional Academic Health Center and Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, Edinburg, Texas, United States of America
⨯
Arshad Khan,

Affiliation Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Lisa Y. Armitige,

Affiliation Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Chinnaswamy Jagannath ,

* E-mail: dhandayutha@uthscsa.edu (SD); Chinnaswamy.Jagannath@uth.tmc.edu (CJ)

Affiliation Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Subramanian Dhandayuthapani

* E-mail: dhandayutha@uthscsa.edu (SD); Chinnaswamy.Jagannath@uth.tmc.edu (CJ)

Affiliation Regional Academic Health Center and Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, Edinburg, Texas, United States of America
⨯

The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages

Sankaralingam Saikolappan,
Jaymie Estrella,
Smitha J. Sasindran,
Arshad Khan,
Lisa Y. Armitige,
Chinnaswamy Jagannath,
Subramanian Dhandayuthapani

Published: May 4, 2012
https://doi.org/10.1371/journal.pone.0036198

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