The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer

Diana L. Esposito; Federica Aru; Rossano Lattanzio; Annalisa Morgano; Michela Abbondanza; Reza Malekzadeh; Faraz Bishehsari; Rosa Valanzano; Antonio Russo; Mauro Piantelli; Antonio Moschetta; Lavinia Vittoria Lotti; Renato Mariani-Costantini

doi:10.1371/journal.pone.0036190

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Open Access

Peer-reviewed

Research Article

The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer

Diana L. Esposito,

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University, Chieti, Italy
⨯
Federica Aru,

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy
⨯
Rossano Lattanzio,

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy
⨯
Annalisa Morgano,

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Laboratory of Lipid Metabolism and Cancer, Department of Translational Pharmacology, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Italy
⨯
Michela Abbondanza,

Affiliation Department of Experimental Medicine, University La Sapienza, Rome, Italy
⨯
Reza Malekzadeh,

Affiliation Digestive Disease Research Center, Shariati Hospital, University of Tehran, Tehran, Iran
⨯
Faraz Bishehsari,

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Digestive Disease Research Center, Shariati Hospital, University of Tehran, Tehran, Iran
⨯
Rosa Valanzano,

Affiliation Department of Clinical Physiopathology, University of Florence, Florence, Italy
⨯
Antonio Russo,

Affiliation Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy
⨯
Mauro Piantelli,

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy
⨯
Antonio Moschetta,

Affiliation Laboratory of Lipid Metabolism and Cancer, Department of Translational Pharmacology, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Italy
⨯
Lavinia Vittoria Lotti,

Affiliation Department of Experimental Medicine, University La Sapienza, Rome, Italy
⨯
Renato Mariani-Costantini

* E-mail: rmc@unich.it

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University, Chieti, Italy
⨯

The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer

Diana L. Esposito,
Federica Aru,
Rossano Lattanzio,
Annalisa Morgano,
Michela Abbondanza,
Reza Malekzadeh,
Faraz Bishehsari,
Rosa Valanzano,
Antonio Russo,
Mauro Piantelli

Published: April 27, 2012
https://doi.org/10.1371/journal.pone.0036190

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