HIV Reservoirs and Immune Surveillance Evasion Cause the Failure of Structured Treatment Interruptions: A Computational Study

Open Access

Peer-reviewed

Research Article

Emiliano Mancini ,

* E-mail: E.Mancini@uva.nl

Affiliation University of Amsterdam, Computational Science, Amsterdam, The Netherlands
⨯
Filippo Castiglione,

Affiliation Institute for Computing Applications Mauro Picone, National Research Council, Roma, Italy
⨯
Massimo Bernaschi,

Affiliation Institute for Computing Applications Mauro Picone, National Research Council, Roma, Italy
⨯
Andrea de Luca,

Affiliations Institute of Clinical Infectious Diseases, Catholic University, Roma, Italy, Infectious Diseases Unit, Siena University Hospital, Siena, Italy
⨯
Peter M. A. Sloot

Affiliations University of Amsterdam, Computational Science, Amsterdam, The Netherlands, National Research University ITMO, Information Technologies, Mechanics and Optics, St. Petersburg, Russia, Nanyang Technological University, Singapore, Singapore
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HIV
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Antiretroviral therapy
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Drug therapy
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HIV infections
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Immune system
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Drug administration
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Opportunistic infections
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Optimization
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