Downregulation of miR-92a Is Associated with Aggressive Breast Cancer Features and Increased Tumour Macrophage Infiltration

Sofie Nilsson; Christina Möller; Karin Jirström; Alexander Lee; Susann Busch; Rebecca Lamb; Göran Landberg

doi:10.1371/journal.pone.0036051

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Open Access

Peer-reviewed

Research Article

Downregulation of miR-92a Is Associated with Aggressive Breast Cancer Features and Increased Tumour Macrophage Infiltration

Sofie Nilsson,

Affiliations Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skåne University Hospital, Malmö, Sweden, Breakthrough Breast Cancer Research Unit, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom
⨯
Christina Möller,

Affiliation Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skåne University Hospital, Malmö, Sweden
⨯
Karin Jirström,

Affiliation Pathology, Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden
⨯
Alexander Lee,

Affiliation Breakthrough Breast Cancer Research Unit, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom
⨯
Susann Busch,

Affiliation Breakthrough Breast Cancer Research Unit, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom
⨯
Rebecca Lamb,

Affiliation Breakthrough Breast Cancer Research Unit, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom
⨯
Göran Landberg

* E-mail: goran.landberg@med.lu.se

Affiliations Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skåne University Hospital, Malmö, Sweden, Breakthrough Breast Cancer Research Unit, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom
⨯

Downregulation of miR-92a Is Associated with Aggressive Breast Cancer Features and Increased Tumour Macrophage Infiltration

Sofie Nilsson,
Christina Möller,
Karin Jirström,
Alexander Lee,
Susann Busch,
Rebecca Lamb,
Göran Landberg

Published: April 26, 2012
https://doi.org/10.1371/journal.pone.0036051

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Breast cancer
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MicroRNAs
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Hepatocellular carcinoma
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In situ hybridization
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Macrophages
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Colorectal cancer
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