YopJ-Induced Caspase-1 Activation in Yersinia-Infected Macrophages: Independent of Apoptosis, Linked to Necrosis, Dispensable for Innate Host Defense

Open Access

Peer-reviewed

Research Article

Ying Zheng,

Affiliation Department of Molecular Genetics and Microbiology, and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, United States of America
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Sarit Lilo,

Current address: Department of Surgery, Stony Brook University, Stony Brook, New York, United States of America

Affiliation Department of Molecular Genetics and Microbiology, and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, United States of America
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Patricio Mena,

Affiliation Department of Molecular Genetics and Microbiology, and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, United States of America
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James B. Bliska

* E-mail: jbliska@ms.cc.sunysb.edu

Affiliation Department of Molecular Genetics and Microbiology, and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, United States of America
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Macrophages
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Apoptosis
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Yersinia pestis
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Necrotic cell death
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Yersinia pseudotuberculosis
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Secretion
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Cytotoxicity
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Necrosis
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