Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

• Sheri L. Bonar ,

  Contributed equally to this work with: Sheri L. Bonar, Susannah D. Brydges, James L. Mueller

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Susannah D. Brydges ,

  Contributed equally to this work with: Sheri L. Bonar, Susannah D. Brydges, James L. Mueller

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• James L. Mueller ,

  Contributed equally to this work with: Sheri L. Bonar, Susannah D. Brydges, James L. Mueller

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Matthew D. McGeough,

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Carla Pena,

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Debbie Chen,

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Susan K. Grimston,

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Cynthia L. Hickman-Brecks,

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Soumya Ravindran,

  Affiliation Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Audrey McAlinden,

  Affiliation Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Deborah V. Novack,

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Daniel L. Kastner,

  Affiliation Medical Genetics Branch, Department of Health and Human Services/National Institutes of Health/National Health Genome Research Institute, Bethesda, Maryland, United States of America

  ⨯
• Roberto Civitelli,

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Hal M. Hoffman ,

  ¶These authors also contributed equally to this work.

  Affiliation Division of Allergy, Immunology, and Rheumatology and Departments of Pediatrics and Medicine, University of California San Diego, La Jolla, California, United States of America

  ⨯
• Gabriel Mbalaviele

  * E-mail: gmbalavi@DOM.wustl.edu

  ¶These authors also contributed equally to this work.

  Affiliation Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯