Assessment of Pseudomonas aeruginosa N5,N10-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

Open Access

Peer-reviewed

Research Article

Assessment of Pseudomonas aeruginosa N⁵,N¹⁰-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

Thomas C. Eadsforth ,

Contributed equally to this work with: Thomas C. Eadsforth, Mary Gardiner
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Mary Gardiner ,

Contributed equally to this work with: Thomas C. Eadsforth, Mary Gardiner
⨯
Fernando V. Maluf,
Stuart McElroy,
Daniel James,
Julie Frearson,
David Gray,
William N. Hunter

* E-mail: w.n.hunter@dundee.ac.uk

Affiliation Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom
⨯

Crystal structure
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Enzyme structure
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Library screening
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Pseudomonas aeruginosa
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Antibacterials
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Enzyme assays
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Drug discovery
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Drug screening
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