Arsenic Induces Functional Re-Expression of Estrogen Receptor α by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer

Juan Du; Nannan Zhou; Hongxia Liu; Fei Jiang; Yubang Wang; Chunyan Hu; Hong Qi; Caiyun Zhong; Xinru Wang; Zhong Li

doi:10.1371/journal.pone.0035957

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Peer-reviewed

Research Article

Arsenic Induces Functional Re-Expression of Estrogen Receptor α by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer

Juan Du ,

Contributed equally to this work with: Juan Du, Nannan Zhou

Affiliation Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Nannan Zhou ,

Contributed equally to this work with: Juan Du, Nannan Zhou

Affiliation Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Hongxia Liu,

Affiliation Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Fei Jiang,

Affiliation Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Yubang Wang,

Affiliations Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China, The Safety Assessment and Research Center for Drugs, Nanjing, Jiangsu Province, China
⨯
Chunyan Hu,

Affiliation Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Hong Qi,

Affiliation Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Caiyun Zhong,

Affiliations Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China, Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Xinru Wang,

Affiliations State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China, Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Zhong Li

* E-mail: uiuclz@126.com

Affiliations State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China, Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, China, Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
⨯

Arsenic Induces Functional Re-Expression of Estrogen Receptor α by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer

Juan Du,
Nannan Zhou,
Hongxia Liu,
Fei Jiang,
Yubang Wang,
Chunyan Hu,
Hong Qi,
Caiyun Zhong,
Xinru Wang,
Zhong Li

Published: April 27, 2012
https://doi.org/10.1371/journal.pone.0035957

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