GFAP-Cre-Mediated Transgenic Activation of Bmi1 Results in Pituitary Tumors

Bart A. Westerman; Marleen Blom; Ellen Tanger; Martin van der Valk; Ji-Ying Song; Marije van Santen; Jules Gadiot; Paulien Cornelissen-Steijger; John Zevenhoven; Haydn M. Prosser; Anthony Uren; Eleonora Aronica; Maarten van Lohuizen

doi:10.1371/journal.pone.0035943

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Open Access

Peer-reviewed

Research Article

GFAP-Cre-Mediated Transgenic Activation of Bmi1 Results in Pituitary Tumors

Bart A. Westerman,

Affiliations Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Department of Oncogenomics, Academic Medical Center, Amsterdam, The Netherlands
⨯
Marleen Blom,

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Ellen Tanger,

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Martin van der Valk,

Affiliation Department of Animal-Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Ji-Ying Song,

Affiliation Department of Animal-Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Marije van Santen,

Affiliation Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
⨯
Jules Gadiot,

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Paulien Cornelissen-Steijger,

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
John Zevenhoven,

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands
⨯
Haydn M. Prosser,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs, United Kingdom
⨯
Anthony Uren,

Affiliations Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Cancer Genomics group at the MRC Clinical Sciences Centre, London, United Kingdom
⨯
Eleonora Aronica,

Affiliation Department of Neuro-Pathology, Academic Medical Center, Amsterdam, The Netherlands
⨯
Maarten van Lohuizen

* E-mail: m.v.lohuizen@nki.nl

Affiliations Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands, The Centre of Biomedical Genetics, Academic Medical Center, Amsterdam, The Netherlands
⨯

GFAP-Cre-Mediated Transgenic Activation of Bmi1 Results in Pituitary Tumors

Bart A. Westerman,
Marleen Blom,
Ellen Tanger,
Martin van der Valk,
Ji-Ying Song,
Marije van Santen,
Jules Gadiot,
Paulien Cornelissen-Steijger,
John Zevenhoven,
Haydn M. Prosser

Published: May 4, 2012
https://doi.org/10.1371/journal.pone.0035943

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