Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular Remodeling

Yosuke Miyazaki; Yasuhiro Ikeda; Kozo Shiraishi; Shizuka N. Fujimoto; Hidekazu Aoyama; Koichi Yoshimura; Makoto Inui; Masahiko Hoshijima; Hideko Kasahara; Hiroki Aoki; Masunori Matsuzaki

doi:10.1371/journal.pone.0035875

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Open Access

Peer-reviewed

Research Article

Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular Remodeling

Yosuke Miyazaki ,

Contributed equally to this work with: Yosuke Miyazaki, Yasuhiro Ikeda

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Yasuhiro Ikeda ,

Contributed equally to this work with: Yosuke Miyazaki, Yasuhiro Ikeda

* E-mail: ysikeda-ymg@umin.ac.jp

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Kozo Shiraishi,

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Shizuka N. Fujimoto,

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Hidekazu Aoyama,

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Koichi Yoshimura,

Affiliation Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Makoto Inui,

Affiliation Department of Pharmacology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯
Masahiko Hoshijima,

Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America
⨯
Hideko Kasahara,

Affiliation Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, United States of America
⨯
Hiroki Aoki,

Affiliation Cardiovascular Research Institute, Kurume University, Kurume, Japan
⨯
Masunori Matsuzaki

Affiliation Department of Medicine and Clinical Science, Division of Cardiology, Yamaguchi University Graduate School of Medicine, Ube, Japan
⨯

Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular Remodeling

Yosuke Miyazaki,
Yasuhiro Ikeda,
Kozo Shiraishi,
Shizuka N. Fujimoto,
Hidekazu Aoyama,
Koichi Yoshimura,
Makoto Inui,
Masahiko Hoshijima,
Hideko Kasahara,
Hiroki Aoki

Published: April 27, 2012
https://doi.org/10.1371/journal.pone.0035875

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