The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of Homologous Recombination Resulting in Mitotic Entry with Unresolved DNA Damage

Open Access

Peer-reviewed

Research Article

Shane Zaidi ,

Contributed equally to this work with: Shane Zaidi, Martin McLaughlin

Affiliation Targeted Therapy Team, Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom
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Martin McLaughlin ,

Contributed equally to this work with: Shane Zaidi, Martin McLaughlin

* E-mail: Martin.McLaughlin@icr.ac.uk

Affiliation Targeted Therapy Team, Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom
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Shreerang A. Bhide,

Affiliation Targeted Therapy Team, Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom
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Suzanne A. Eccles,

Affiliation Tumour Biology and Metastasis Team, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, Haddow Laboratories, Sutton, Surrey, United Kingdom
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Paul Workman,

Affiliation Signal Transduction and Molecular Pharmacology Team, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, Haddow Laboratories, Sutton, Surrey, United Kingdom
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Christopher M. Nutting,

Affiliation The Royal Marsden Hospital, London, United Kingdom
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Robert A. Huddart,

Affiliation The Royal Marsden Hospital, Sutton, United Kingdom
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Kevin J. Harrington

Affiliations Targeted Therapy Team, Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom, The Royal Marsden Hospital, London, United Kingdom
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