Early Treatment with Fumagillin, an Inhibitor of Methionine Aminopeptidase-2, Prevents Pulmonary Hypertension in Monocrotaline-Injured Rats

• Daniel J. Kass ,

  * E-mail: kassd2@upmc.edu

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania, United States of America

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• Eileen Rattigan,

  Affiliation Department of Cardiology, Geisinger Health System, Wilkes-Barre, Pennsylvania, United States of America

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• Rehan Kahloon,

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania, United States of America

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• Katrina Loh,

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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• Liyang Yu,

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania, United States of America

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• Asaf Savir,

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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• Mark Markowski,

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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• Anjali Saqi,

  Affiliation Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

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• Revathi Rajkumar,

  Affiliation Department of Medicine, Cardiovascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Ferhaan Ahmad,

  Affiliations Department of Medicine, Cardiovascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Hunter C. Champion

  Affiliations Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania, United States of America, Department of Medicine, Cardiovascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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