In Vitro and In Vivo Antagonism of a G Protein-Coupled Receptor (S1P3) with a Novel Blocking Monoclonal Antibody

Open Access

Peer-reviewed

Research Article

In Vitro and In Vivo Antagonism of a G Protein-Coupled Receptor (S1P₃) with a Novel Blocking Monoclonal Antibody

Greg L. Harris,

Affiliations Expression Drug Designs, LLC, San Marcos, California, United States of America, Department of Biology, San Diego State University, San Diego, California, United States of America
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Michael B. Creason,

Affiliation Expression Drug Designs, LLC, San Marcos, California, United States of America
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Greg B. Brulte,

Affiliation Expression Drug Designs, LLC, San Marcos, California, United States of America
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Deron R. Herr

* E-mail: dherr@expressiondrugdesigns.com

Affiliations Expression Drug Designs, LLC, San Marcos, California, United States of America, Department of Biology, San Diego State University, San Diego, California, United States of America
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Cancer treatment
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Breast cancer
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G protein coupled receptors
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Breast tumors
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Inflammation
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Transfection
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Antibody therapy
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Mouse models
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