Acute Activation of AMP-Activated Protein Kinase Prevents H2O2-Induced Premature Senescence in Primary Human Keratinocytes

Open Access

Peer-reviewed

Research Article

Acute Activation of AMP-Activated Protein Kinase Prevents H₂O₂-Induced Premature Senescence in Primary Human Keratinocytes

Yasuo Ido ,

* E-mail: nrude@bu.edu (NR); yido@bu.edu (YI)

Affiliation Section of Endocrinology and Diabetes Research Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Albert Duranton,

Affiliation L'OREAL Recherche, Centre Charles Zviak, Clichy, France
⨯
Fan Lan,

Affiliation Section of Endocrinology and Diabetes Research Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
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Jose M. Cacicedo,

Affiliation Section of Endocrinology and Diabetes Research Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
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Tai C. Chen,

Affiliation Section of Endocrinology and Diabetes Research Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
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Lionel Breton,

Affiliation L'OREAL Recherche, Centre Charles Zviak, Clichy, France
⨯
Neil B. Ruderman

* E-mail: nrude@bu.edu (NR); yido@bu.edu (YI)

Affiliation Section of Endocrinology and Diabetes Research Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯

Keratinocytes
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Phosphorylation
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Senescence
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Hydrogen peroxide
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Fibroblasts
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Adenoviruses
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Transactivation
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Lentivirus
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