Comparative Transcriptional Network Modeling of Three PPAR-α/γ Co-Agonists Reveals Distinct Metabolic Gene Signatures in Primary Human Hepatocytes

• Renée Deehan,

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• Pia Maerz-Weiss,

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Natalie L. Catlett,

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• Guido Steiner,

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Ben Wong,

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• Matthew B. Wright ,

  * E-mail: matthew.wright@roche.com

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Gil Blander,

  Current address: Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• Keith O. Elliston,

  Current address: CHDI Foundation, Princeton, New Jersey, United States of America

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• William Ladd,

  Affiliation Selventa, Cambridge, Massachusetts, United States of America

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• Maria Bobadilla,

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Jacques Mizrahi,

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Carolina Haefliger,

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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• Alan Edgar

  ¶† Deceased.

  Affiliation F. Hoffmann-La Roche AG, Basel, Switzerland

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