Tibial Loading Increases Osteogenic Gene Expression and Cortical Bone Volume in Mature and Middle-Aged Mice

• Matthew J. Silva ,

  * E-mail: silvam@wustl.edu

  Affiliations Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America, Department of Biomedical Engineering, Washington University, St. Louis, Missouri, United States of America

  ⨯
• Michael D. Brodt,

  Affiliation Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America

  ⨯
• Michelle A. Lynch,

  Affiliation Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America

  ⨯
• Abby L. Stephens,

  Affiliations Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America, Department of Biomedical Engineering, Washington University, St. Louis, Missouri, United States of America

  ⨯
• Daniel J. Wood,

  Affiliation Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America

  ⨯
• Roberto Civitelli

  Affiliation Department of Internal Medicine, Washington University, St. Louis, Missouri, United States of America

  ⨯