Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

Nicole Testerink; Mokrish Ajat; Martin Houweling; Jos F. Brouwers; Vishnu V. Pully; Henk-Jan van Manen; Cees Otto; J. Bernd Helms; Arie B. Vaandrager

doi:10.1371/journal.pone.0034945

Loading metrics

Open Access

Peer-reviewed

Research Article

Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

Nicole Testerink,

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯
Mokrish Ajat,

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯
Martin Houweling,

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯
Jos F. Brouwers,

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯
Vishnu V. Pully,

Current address: Philips Research, Eindhoven, The Netherlands

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands
⨯
Henk-Jan van Manen,

Current address: Department of Development and Innovation Expert Capability Group-Measurement & Analytical Science, AkzoNobel Research, Deventer, The Netherlands

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands
⨯
Cees Otto,

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands
⨯
J. Bernd Helms,

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯
Arie B. Vaandrager

* E-mail: A.B.Vaandrager@uu.nl

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands
⨯

Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

Nicole Testerink,
Mokrish Ajat,
Martin Houweling,
Jos F. Brouwers,
Vishnu V. Pully,
Henk-Jan van Manen,
Cees Otto,
J. Bernd Helms,
Arie B. Vaandrager

Published: April 20, 2012
https://doi.org/10.1371/journal.pone.0034945

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Fatty acids
Is the Subject Area "Fatty acids" applicable to this article?

Thanks for your feedback.
Esters
Is the Subject Area "Esters" applicable to this article?

Thanks for your feedback.
Neutral lipids
Is the Subject Area "Neutral lipids" applicable to this article?

Thanks for your feedback.
Phospholipids
Is the Subject Area "Phospholipids" applicable to this article?

Thanks for your feedback.
Liquid chromatography-mass spectrometry
Is the Subject Area "Liquid chromatography-mass spectrometry" applicable to this article?

Thanks for your feedback.
Fluorescence microscopy
Is the Subject Area "Fluorescence microscopy" applicable to this article?

Thanks for your feedback.
Lipid analysis
Is the Subject Area "Lipid analysis" applicable to this article?

Thanks for your feedback.