Common Genetic Denominators for Ca++-Based Skeleton in Metazoa: Role of Osteoclast-Stimulating Factor and of Carbonic Anhydrase in a Calcareous Sponge

Werner E. G. Müller; Xiaohong Wang; Vlad A. Grebenjuk; Michael Korzhev; Matthias Wiens; Ute Schloßmacher; Heinz C. Schröder

doi:10.1371/journal.pone.0034617

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Peer-reviewed

Research Article

Common Genetic Denominators for Ca⁺⁺-Based Skeleton in Metazoa: Role of Osteoclast-Stimulating Factor and of Carbonic Anhydrase in a Calcareous Sponge

Werner E. G. Müller ,

* E-mail: wmueller@uni-mainz.de

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯
Xiaohong Wang,

Affiliations ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, National Research Center for Geoanalysis, Chinese Academy of Geological Sciences, CHN-Beijing, China
⨯
Vlad A. Grebenjuk,

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯
Michael Korzhev,

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯
Matthias Wiens,

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯
Ute Schloßmacher,

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯
Heinz C. Schröder

Affiliation ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⨯

Common Genetic Denominators for Ca⁺⁺-Based Skeleton in Metazoa: Role of Osteoclast-Stimulating Factor and of Carbonic Anhydrase in a Calcareous Sponge

Werner E. G. Müller,
Xiaohong Wang,
Vlad A. Grebenjuk,
Michael Korzhev,
Matthias Wiens,
Ute Schloßmacher,
Heinz C. Schröder

Published: April 10, 2012
https://doi.org/10.1371/journal.pone.0034617

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Carbonic anhydrases
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Phage display
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Sponges
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Polypeptides
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Gene expression
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Osteoclasts
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DAPI staining
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Recombinant proteins
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