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Open Access
Peer-reviewed
Research Article
Efficacy of a Non-Hypercalcemic Vitamin-D2 Derived Anti-Cancer Agent (MT19c) and Inhibition of Fatty Acid Synthesis in an Ovarian Cancer Xenograft Model
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Richard G. Moore,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Thilo S. Lange,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Katina Robinson,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Kyu K. Kim,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Alper Uzun,
Affiliation Center for Computational Molecular Biology, Department of Pediatrics, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Timothy C. Horan,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Nada Kawar,
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Naohiro Yano,
Affiliation Department of Pediatrics, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Sharon R. Chu,
Affiliation Developmental Pathology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Quanfu Mao,
Affiliation Developmental Pathology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Laurent Brard,
Affiliation Gynecology Oncology, Southern Illinois Medical School, Springfield, Illinois, United States of America
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Monique E. DePaepe,
Affiliation Developmental Pathology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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James F. Padbury,
Affiliation Center for Computational Molecular Biology, Department of Pediatrics, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Leggy A. Arnold,
Affiliation Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
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Alexander Brodsky,
Affiliation Department of Biology and Medicine, Brown University, Providence, Rhode Island, United States of America
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Tun-Li Shen,
Affiliation Department of Chemistry, Brown University, Providence, Rhode Island, United States of America
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Rakesh K. Singh
* E-mail: rsingh@wihri.org
Affiliation Molecular Therapeutics Laboratory, Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, Alpert Medical School, Brown University, Providence, Rhode Island, United States of America
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Efficacy of a Non-Hypercalcemic Vitamin-D2 Derived Anti-Cancer Agent (MT19c) and Inhibition of Fatty Acid Synthesis in an Ovarian Cancer Xenograft Model
- Richard G. Moore,
- Thilo S. Lange,
- Katina Robinson,
- Kyu K. Kim,
- Alper Uzun,
- Timothy C. Horan,
- Nada Kawar,
- Naohiro Yano,
- Sharon R. Chu,
- Quanfu Mao
- Published: April 3, 2012
- https://doi.org/10.1371/journal.pone.0034443