Effects of Vagus Nerve Stimulation and Vagotomy on Systemic and Pulmonary Inflammation in a Two-Hit Model in Rats

Open Access

Peer-reviewed

Research Article

Matthijs Kox ,

* E-mail: m.kox@ic.umcn.nl

Affiliations Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands
⨯
Michiel Vaneker,

Affiliation Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Johannes G. van der Hoeven,

Affiliations Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands
⨯
Gert-Jan Scheffer,

Affiliation Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Cornelia W. Hoedemaekers,

Affiliation Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Peter Pickkers

Affiliations Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands
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Inflammation
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Breathing
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Cytokines
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Vagotomy
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Tidal volume
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Blood pressure
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Functional electrical stimulation
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Systemic inflammatory response syndrome
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