Host Immune Transcriptional Profiles Reflect the Variability in Clinical Disease Manifestations in Patients with Staphylococcus aureus Infections

Romain Banchereau; Alejandro Jordan-Villegas; Monica Ardura; Asuncion Mejias; Nicole Baldwin; Hui Xu; Elizabeth Saye; Jose Rossello-Urgell; Phuong Nguyen; Derek Blankenship; Clarence B. Creech; Virginia Pascual; Jacques Banchereau; Damien Chaussabel; Octavio Ramilo

doi:10.1371/journal.pone.0034390

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Open Access

Peer-reviewed

Research Article

Host Immune Transcriptional Profiles Reflect the Variability in Clinical Disease Manifestations in Patients with Staphylococcus aureus Infections

Romain Banchereau ,

* E-mail: romain.banchereau@utsouthwestern.edu

Affiliation UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Alejandro Jordan-Villegas,

Affiliation UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Monica Ardura,

Affiliation Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Asuncion Mejias,

Affiliation Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Nicole Baldwin,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Hui Xu,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Elizabeth Saye,

Affiliation Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Jose Rossello-Urgell,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Phuong Nguyen,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Derek Blankenship,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Clarence B. Creech,

Affiliation Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Virginia Pascual,

Affiliation Baylor Institute for Immunology Research, Dallas, Texas, United States of America
⨯
Jacques Banchereau,

Affiliations Baylor Institute for Immunology Research, Dallas, Texas, United States of America, Hoffmann-Laroche, Nutley, New Jersey, United States of America
⨯
Damien Chaussabel,

Affiliations Baylor Institute for Immunology Research, Dallas, Texas, United States of America, Benaroya Research Institute, Seattle, Washington, United States of America
⨯
Octavio Ramilo

Affiliation Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯

Host Immune Transcriptional Profiles Reflect the Variability in Clinical Disease Manifestations in Patients with Staphylococcus aureus Infections

Romain Banchereau,
Alejandro Jordan-Villegas,
Monica Ardura,
Asuncion Mejias,
Nicole Baldwin,
Hui Xu,
Elizabeth Saye,
Jose Rossello-Urgell,
Phuong Nguyen,
Derek Blankenship

Published: April 4, 2012
https://doi.org/10.1371/journal.pone.0034390

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Staphylococcus aureus
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Pneumonia
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Blood
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Hierarchical clustering
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Blood counts
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Staphylococcal infection
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