Mitochondrial Dysfunction and Adipogenic Reduction by Prohibitin Silencing in 3T3-L1 Cells

Dong Liu; Yiming Lin; Ting Kang; Bo Huang; Wei Xu; Minerva Garcia-Barrio; Moshood Olatinwo; Roland Matthews; Y. Eugene Chen; Winston E. Thompson

doi:10.1371/journal.pone.0034315

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Open Access

Peer-reviewed

Research Article

Mitochondrial Dysfunction and Adipogenic Reduction by Prohibitin Silencing in 3T3-L1 Cells

Dong Liu ,

* E-mail: dliu@msm.edu (DL); wthompson@msm.edu (WET)

Affiliations Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia, United States of America, Department of Physiology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯
Yiming Lin,

Affiliation Department of Endocrinology, School of Medicine, Emory University, Atlanta, Georgia, United States of America
⨯
Ting Kang,

Affiliations Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia, United States of America, Division of Cardiology, the First Affiliated Hospital, Nanchang University, Nanchang, China
⨯
Bo Huang,

Affiliations Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia, United States of America, Department of Clinical Laboratory Sciences, the Second Affiliated Hospital, Nanchang University, Nanchang, China
⨯
Wei Xu,

Affiliation Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯
Minerva Garcia-Barrio,

Affiliation Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯
Moshood Olatinwo,

Affiliation Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯
Roland Matthews,

Affiliation Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯
Y. Eugene Chen,

Affiliation Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Winston E. Thompson

* E-mail: dliu@msm.edu (DL); wthompson@msm.edu (WET)

Affiliation Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia, United States of America
⨯

Mitochondrial Dysfunction and Adipogenic Reduction by Prohibitin Silencing in 3T3-L1 Cells

Dong Liu,
Yiming Lin,
Ting Kang,
Bo Huang,
Wei Xu,
Minerva Garcia-Barrio,
Moshood Olatinwo,
Roland Matthews,
Y. Eugene Chen,
Winston E. Thompson

Published: March 30, 2012
https://doi.org/10.1371/journal.pone.0034315

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Mitochondria
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Adipocyte differentiation
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Small interfering RNA
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Transfection
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Mitochondrial DNA
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Adipose tissue
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Immunoblotting
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