Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling

Open Access

Peer-reviewed

Research Article

Zhijie Lin,

Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, College of Life Sciences, Nankai University, Tianjin, China
⨯
Jing Lu,

Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, College of Life Sciences, Nankai University, Tianjin, China
⨯
Weihong Zhou,

Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, College of Life Sciences, Nankai University, Tianjin, China
⨯
Yuequan Shen

* E-mail: yuequan74@yahoo.com

Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, College of Life Sciences, Nankai University, Tianjin, China
⨯

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Crystal structure
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Dimers
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Transcription factors
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Monomers
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Glutathione chromatography
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Toll-like receptors
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Immune receptor signaling
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Luciferase assay
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