A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

Houda Z. Elloumi; Nitsan Maharshak; Kavitha N. Rao; Taku Kobayashi; Hyungjin S. Ryu; Marcus Mühlbauer; Fengling Li; Christian Jobin; Scott E. Plevy

doi:10.1371/journal.pone.0034172

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Research Article

A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

Houda Z. Elloumi ,

Contributed equally to this work with: Houda Z. Elloumi, Nitsan Maharshak, Kavitha N. Rao

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Nitsan Maharshak ,

Contributed equally to this work with: Houda Z. Elloumi, Nitsan Maharshak, Kavitha N. Rao

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Kavitha N. Rao ,

Contributed equally to this work with: Houda Z. Elloumi, Nitsan Maharshak, Kavitha N. Rao

Affiliation Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Taku Kobayashi,

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Hyungjin S. Ryu,

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Marcus Mühlbauer,

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Fengling Li,

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Christian Jobin,

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯
Scott E. Plevy

* E-mail: scott_plevy@med.unc.edu

Affiliation Center for Gastrointestinal Biology and Diseases, Departments of Medicine and Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
⨯

A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

Houda Z. Elloumi,
Nitsan Maharshak,
Kavitha N. Rao,
Taku Kobayashi,
Hyungjin S. Ryu,
Marcus Mühlbauer,
Fengling Li,
Christian Jobin,
Scott E. Plevy

Published: March 27, 2012
https://doi.org/10.1371/journal.pone.0034172

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Colitis
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Colon
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T cells
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Gene expression
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