Overexpression of the Catalytically Impaired Taspase1T234V or Taspase1D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia Cells

Carolin Bier; Rouven Hecht; Lena Kunst; Sabine Scheiding; Désirée Wünsch; Dorothée Goesswein; Günter Schneider; Oliver H. Krämer; Shirley K. Knauer; Roland H. Stauber

doi:10.1371/journal.pone.0034142

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Peer-reviewed

Research Article

Overexpression of the Catalytically Impaired Taspase1^T234V or Taspase1^D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia Cells

Carolin Bier ,

* E-mail: bier@uni-mainz.de (CB); shirley.knauer@uni-due.de (SK); rstauber@uni-mainz.de (RS)

Affiliation Molecular and Cellular Oncology, Mainz Screening Center (MSC), University Hospital of Mainz, Mainz, Germany
⨯
Rouven Hecht,

Affiliation Institute for Molecular Biology, Center for Medical Biotechnology (ZMB), University Duisburg-Essen, Essen, Germany
⨯
Lena Kunst,

Affiliation Institute for Molecular Biology, Center for Medical Biotechnology (ZMB), University Duisburg-Essen, Essen, Germany
⨯
Sabine Scheiding,

Affiliation Institute for Biochemistry and Biophysics/Centre for Molecular Biomedicine (CMB), Friedrich-Schiller-University Jena, Jena, Germany
⨯
Désirée Wünsch,

Affiliation Molecular and Cellular Oncology, Mainz Screening Center (MSC), University Hospital of Mainz, Mainz, Germany
⨯
Dorothée Goesswein,

Affiliation Molecular and Cellular Oncology, Mainz Screening Center (MSC), University Hospital of Mainz, Mainz, Germany
⨯
Günter Schneider,

Affiliation Department of Internal Medicine II, Technical University of Munich, Munich, Germany
⨯
Oliver H. Krämer,

Affiliation Institute for Biochemistry and Biophysics/Centre for Molecular Biomedicine (CMB), Friedrich-Schiller-University Jena, Jena, Germany
⨯
Shirley K. Knauer ,

* E-mail: bier@uni-mainz.de (CB); shirley.knauer@uni-due.de (SK); rstauber@uni-mainz.de (RS)

Affiliation Institute for Molecular Biology, Center for Medical Biotechnology (ZMB), University Duisburg-Essen, Essen, Germany
⨯
Roland H. Stauber

* E-mail: bier@uni-mainz.de (CB); shirley.knauer@uni-due.de (SK); rstauber@uni-mainz.de (RS)

Affiliation Molecular and Cellular Oncology, Mainz Screening Center (MSC), University Hospital of Mainz, Mainz, Germany
⨯

Overexpression of the Catalytically Impaired Taspase1^T234V or Taspase1^D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia Cells

Carolin Bier,
Rouven Hecht,
Lena Kunst,
Sabine Scheiding,
Désirée Wünsch,
Dorothée Goesswein,
Günter Schneider,
Oliver H. Krämer,
Shirley K. Knauer,
Roland H. Stauber

Published: May 3, 2012
https://doi.org/10.1371/journal.pone.0034142

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