Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption

• An Qin ,

  Contributed equally to this work with: An Qin, Tak S. Cheng

  Affiliations Shanghai Key Laboratory of Orthopaedic Implant, Department of Orthopaedics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, The People's Republic of China, Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Western Australia, Australia

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• Tak S. Cheng ,

  Contributed equally to this work with: An Qin, Tak S. Cheng

  Affiliation Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Western Australia, Australia

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• Zhen Lin,

  Affiliations Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Western Australia, Australia, Division of Orthopaedic, Department of Surgery, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangdong, The People's Republic of China

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• Lei Cao,

  Affiliation Shanghai Key Laboratory of Orthopaedic Implant, Department of Orthopaedics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, The People's Republic of China

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• Shek M. Chim,

  Affiliation School of Pathology and Laboratory Medicine, The University of Western Australia, Western Australia, Australia

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• Nathan J. Pavlos,

  Affiliation Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Western Australia, Australia

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• Jiake Xu,

  Affiliation School of Pathology and Laboratory Medicine, The University of Western Australia, Western Australia, Australia

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• Ming Hao Zheng ,

  * E-mail: minghao.zheng@uwa.edu.au (MZ); krdai@163.com (KD)

  Affiliation Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Western Australia, Australia

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• Ke Rong Dai

  * E-mail: minghao.zheng@uwa.edu.au (MZ); krdai@163.com (KD)

  Affiliations Shanghai Key Laboratory of Orthopaedic Implant, Department of Orthopaedics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, The People's Republic of China, Orthopaedic Cellular and Molecular Biology Laboratory, Institute of Health Sciences, School of Medicine, Chinese Academy of Sciences, Shanghai Jiao Tong University, Shanghai, The People's Republic of China

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